Percocet E712 (Oxycodone / APAP 10/325mg)
Dual-mechanism combination analgesic combining short-acting oxycodone with acetaminophen for moderate-to-severe acute pain relief.
Price range: $299.00 through $1,049.00
Direct from certified manufacturers in sealed blister packs.
Plain unmarked outer box with zero medicine identifiers.
Dispatched in 24-48h with secure end-to-end tracking.
Assistance anytime via vitalrxcare@gmail.com.
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
Clinical Reference Monograph: Oxycodone & Acetaminophen 10mg/325mg (Percocet E712)
| Active Ingredient | Oxycodone Hydrochloride 10 mg + Acetaminophen (APAP) 325 mg |
|---|---|
| Originator / Brand | Endocet (Endo Pharmaceuticals) / Percocet equivalent |
| Dosage Form | Yellow oval tablet imprinted E712 on one side and 10/325 on reverse |
| Controlled Schedule | DEA Schedule II Controlled Substance (US) / Class A (UK) |
|---|---|
| Primary Indication | Short-term management of acute moderate-to-severe pain requiring an opioid |
| Standard Dosing | One tablet every 4 to 6 hours as needed; maximum 6 tablets per 24 hours |
1. Mechanism of Action & Therapeutic Use
Synergistic dual-analgesic mechanism: oxycodone acts centrally on mu-opioid pathways while acetaminophen inhibits prostaglandin synthesis centrally and peripheral pain impulse generation.
2. Prescribed Administration Guidelines
- Take only as prescribed for acute short-term pain episodes.
- Do not exceed 4,000 mg total daily acetaminophen from all sources (prescription & OTC).
- Avoid combining with cold, flu, or headache remedies containing paracetamol.
- Take with food or milk if gastrointestinal nausea occurs.
Acetaminophen has been associated with acute liver failure, sometimes resulting in liver transplant or death, frequently linked to ingestion exceeding daily limits. Concomitant opioid risks include fatal respiratory depression and addiction.
3. Safety Precautions & Contraindications
Strict Contraindications: Hypersensitivity to oxycodone or acetaminophen; severe hepatic impairment; severe respiratory depression; acute asthma; bowel obstruction.
4. Adverse Reactions Profile
Common & Transient Effects:
Nausea, constipation, dizziness, somnolence, lightheadedness, diaphoresis.
Serious Reactions (Urgent Medical Evaluation):
Opioid overdose (respiratory depression, cyanosis), liver injury (upper-right abdominal pain, jaundice, dark urine).
5. Clinically Significant Drug Interactions
Alcohol markedly accelerates hepatotoxicity and respiratory depression. Benzodiazepines and sedatives compound lethargy.
6. Proper Storage & Security
Store at 20°C to 25°C away from moisture. Keep locked away from children and unauthorized individuals.
| Pack Size | 60 Tablets, 90 Tablets, 180 Tablets |
|---|
Clinical Reference Monograph: Oxycodone & Acetaminophen 10mg/325mg (Percocet E712)
| Active Ingredient | Oxycodone Hydrochloride 10 mg + Acetaminophen (APAP) 325 mg |
|---|---|
| Originator / Brand | Endocet (Endo Pharmaceuticals) / Percocet equivalent |
| Dosage Form | Yellow oval tablet imprinted E712 on one side and 10/325 on reverse |
| Controlled Schedule | DEA Schedule II Controlled Substance (US) / Class A (UK) |
|---|---|
| Primary Indication | Short-term management of acute moderate-to-severe pain requiring an opioid |
| Standard Dosing | One tablet every 4 to 6 hours as needed; maximum 6 tablets per 24 hours |
1. Mechanism of Action & Therapeutic Use
Synergistic dual-analgesic mechanism: oxycodone acts centrally on mu-opioid pathways while acetaminophen inhibits prostaglandin synthesis centrally and peripheral pain impulse generation.
2. Prescribed Administration Guidelines
- Take only as prescribed for acute short-term pain episodes.
- Do not exceed 4,000 mg total daily acetaminophen from all sources (prescription & OTC).
- Avoid combining with cold, flu, or headache remedies containing paracetamol.
- Take with food or milk if gastrointestinal nausea occurs.
Acetaminophen has been associated with acute liver failure, sometimes resulting in liver transplant or death, frequently linked to ingestion exceeding daily limits. Concomitant opioid risks include fatal respiratory depression and addiction.
3. Safety Precautions & Contraindications
Strict Contraindications: Hypersensitivity to oxycodone or acetaminophen; severe hepatic impairment; severe respiratory depression; acute asthma; bowel obstruction.
4. Adverse Reactions Profile
Common & Transient Effects:
Nausea, constipation, dizziness, somnolence, lightheadedness, diaphoresis.
Serious Reactions (Urgent Medical Evaluation):
Opioid overdose (respiratory depression, cyanosis), liver injury (upper-right abdominal pain, jaundice, dark urine).
5. Clinically Significant Drug Interactions
Alcohol markedly accelerates hepatotoxicity and respiratory depression. Benzodiazepines and sedatives compound lethargy.
6. Proper Storage & Security
Store at 20°C to 25°C away from moisture. Keep locked away from children and unauthorized individuals.
Medication & Fulfillment FAQ
All orders are packed in discreet, heavy-duty unmarked protective boxes with tamper-evident seals. For complete patient privacy, there is zero mention of pharmacy names, medication types, or contents on the shipping label. Shipments are sent via express tracked courier service, and tracking numbers are emailed upon dispatch.
VitalRxCare only provides medications sourced from verified, licensed pharmaceutical manufacturers. Each medication includes authentic manufacturer batch lot numbers, expiration dates, and verifiable NDC or manufacturing imprints. Please review the detailed Clinical Monograph and Identification table on this page for verified active chemical constituents.
To accommodate both initial courses and ongoing maintenance therapies, we provide transparent supply tiers: 60-count (starter supply), 90-count (standard 3-month course), and 180-count (extended 6-month value pack). Volume discounts are automatically applied to 90 and 180 pill packages, lowering your per-tablet cost.
Our dedicated patient support team is available 24/7 to answer fulfillment inquiries, payment questions, and order tracking updates. You can reach our support team directly at vitalrxcare@gmail.com or via our secure Contact page. Inquiries are generally responded to within 1 to 2 business hours.
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